Thermo Fisher Scientific TOR2A Polyclonal Antibody
TOR2A 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS와 50% glycerol 용액에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Torsin 2A (amino acids 34–293 of target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903969 |
Target Information
Salusins are multifunctional bioactive peptides discovered through bioinformatics analysis of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids, respectively. These peptides are believed to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), through frameshift reading and cleavage at dibasic amino acids.
Salusin alpha has been implicated in atherosclerosis by suppressing acyl-CoA:cholesterol acyltransferase-1, which converts free cholesterol into cholesterol esters in macrophages, thereby reducing foam cell formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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