Thermo Fisher Scientific DJ-1 Polyclonal Antibody
DJ-1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, IP 등 다양한 응용에 적합함. 인간 및 생쥐 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 산화 스트레스 관련 연구 및 파킨슨병 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 140 and the C-terminus (residue 189) of human DJ-1 (PARK7, Parkinson Disease 7) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
Target Information
The DJ-1 gene product belongs to the peptidase C56 family. It acts as a positive regulator of androgen receptor-dependent transcription and may function as a redox-sensitive chaperone and oxidative stress sensor. It protects neurons against oxidative stress and cell death. Defects in this gene cause autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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