Thermo Fisher Scientific DEFA1 Monoclonal Antibody (2D2)
Human DEFA1 단백질을 인식하는 Mouse monoclonal antibody (Clone 2D2). Western blot과 IHC(P)에서 검증됨. Protein G로 정제된 액상형 항체로, PBS/glycerol buffer에 보관. 인체 면역 방어 관련 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D2 |
| Immunogen | Synthetic peptide within Human HNP-1 (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2848800 |
Product Specific Information
- Positive Control: Rat spleen tissue, Human spleen tissue
Target Information
Defensins are a family of microbicidal and cytotoxic peptides involved in host defense. They are abundant in neutrophil granules and epithelial tissues such as the intestine, respiratory tract, urinary tract, and vagina. Members of this family share a conserved cysteine motif.
The DEFA1 gene encodes defensin alpha 1, found in neutrophil granules and involved in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8, and DEFA1 differs from DEFA3 by only one amino acid. Both genes are subject to copy number variation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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