Thermo Fisher Scientific RBL1 Polyclonal Antibody
RBL1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot에 최적화됨. Human 종에 반응하며, 항원 친화 크로마토그래피로 정제됨. 고농도 액상 형태로 안정적이며, 장기 보관 시 -20°C 이하 권장.
- 카탈로그번호
- PA5119584
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human p107 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.78 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913157 |
Product Specific Information
Store as concentrated solution. Centrifuge briefly prior to opening vial.
For short-term storage (1–2 weeks), store at 4°C.
For long-term storage, aliquot and store at -20°C or below.
Avoid multiple freeze-thaw cycles.
Target Information
RB-like 1 (RBL1) is similar in sequence and possibly in function to the retinoblastoma 1 (RB1) gene product.
RB1 is a tumor suppressor protein involved in cell cycle regulation, phosphorylated during the S to M phase transition and dephosphorylated in G1 phase.
Both RB1 and RB-like 1 can form complexes with adenovirus E1A and SV40 large T-antigen, binding only in the unphosphorylated state.
They inhibit transcription of cell cycle genes containing E2F binding sites, suggesting that RB-like 1 also acts as a tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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