Thermo Fisher Scientific SFRP1 Recombinant Rabbit Monoclonal Antibody (ARC1683)
SFRP1 단백질을 표적으로 하는 재조합 토끼 단일클론 항체로, Western blot, ELISA, IP에 사용 가능. 인간, 마우스, 랫트 반응성. HEK293 세포 발현, 액상 형태, 고순도 친화 크로마토그래피 정제. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| ELISA | 1 µg/mL | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1683 |
| Immunogen | A synthetic peptide corresponding to amino acids 1–100 of human SFRP1 (Q8N474) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.88 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898110 |
Product Specific Information
- Positive Samples: U-251MG, Mouse kidney, Rat testis, Rat kidney
- Immunogen sequence:
MGIGRSEGGR RGAALGVLLA LGAALLAVGS ASEYDYVSFQ SDIGPYQSGR FYTKPPQCVD IPADLRLCHN VGYKKMVLPN LLEHETMAEV KQQASSWVPL
Target Information
Secreted frizzled-related protein 1 (SFRP1) is a member of the SFRP family containing a cysteine-rich domain homologous to the Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling.
SFRP1 and SFRP5 may be involved in determining the polarity of photoreceptor cells in the retina.
SFRP1 is expressed in several human tissues, with the highest levels in the heart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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