Thermo Fisher Scientific Rad17 Polyclonal Antibody
Rad17 단백질을 인식하는 Thermo Fisher Scientific의 goat polyclonal antibody. Western blot과 immunoprecipitation에 적합하며 인간 시료에 반응. 항원 친화 크로마토그래피로 정제된 액상 형태, 4°C 보관. DNA 손상 체크포인트 연구용에 적합.
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Thermo Fisher Scientific Rad17 Polyclonal Antibody
Applications
- Western Blot (WB): 1:2,000–1:10,000
- Immunoprecipitation (IP): 40 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 564 and 614 of human RAD17 checkpoint clamp loader component |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7.0–8.0 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Predicted reactivity by homology: Orangutan
Target Information
Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage.
It exhibits weak ATPase activity required for chromatin binding and participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, contributing to CHEK1 activation.
Rad17 may also serve as a sensor of DNA replication progression and be involved in homologous recombination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(A305-788A_RAD17_O75943-1_Goat.svg 및 A305-788A_RAD17_O75943-1_Goat_PDP.jpeg 이미지 참조)
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