Thermo Fisher Scientific Rad17 Polyclonal Antibody
RAD17 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 다클론 항체. Western blot 및 면역침강(IP)에 적합하며, 인간 RAD17(564–614) 영역을 면역원으로 사용. 세포 성장과 DNA 손상 체크포인트 연구에 활용 가능.
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Thermo Fisher Scientific Rad17 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:2,000–1:10,000
- Immunoprecipitation (IP): 40 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 564 and 614 of human RAD17 checkpoint clamp loader component |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
Predicted reactivity by homology: Orangutan.
Target Information
Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage.
It has a weak ATPase activity required for binding to chromatin.
Rad17 participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation.
It may also serve as a sensor of DNA replication progression and may be involved in homologous recombination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: A305-788A-M_RAD17_O75943-1_Goat.svg, A305-788A-M_RAD17_O75943-1_Goat_PDP.jpeg)
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