Thermo Fisher Scientific LRRK2 Polyclonal Antibody
LRRK2 단백질을 표적하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot 및 IHC에 사용 가능하며, 인간 시료에 반응합니다. 합성 펩타이드를 면역원으로 사용하였으며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Thermo Fisher Scientific LRRK2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:200–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Goat / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from internal region of human Dardarin (LRRK2, PARK8) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 150 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: Dardarin.
Target Information
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain.
Mutations in LRRK2 have been associated with Parkinson’s disease.
LRRK2 encodes a protein with multiple functional regions, including ankyrin repeat, LRR, kinase, DFG-like motif, RAS, GTPase, MLK-like, and WD40 domains.
The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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