Thermo Fisher Scientific Phospho-MAPKAPK2 (Thr334) Recombinant Rabbit Monoclonal Antibody (MAPKAPK2T334-H2)
Recombinant rabbit monoclonal antibody recognizing phospho-MAPKAPK2 (Thr334). Validated for WB and Flow Cytometry. Offers high specificity, lot-to-lot consistency, and animal origin-free formulation. Suitable for studying p38/ERK signaling and stress r...
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Flow Cytometry (Flow) | 1–1,000 ng/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MAPKAPK2T334-H2 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Thr334 of human phospho MAPKAPK-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896945 |
Available Conjugated Formats
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and expressed in HEK293 cells. Individual clones are screened to select the best candidates for production.
Key advantages:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to large rabbit immune repertoire
Target Information
MAPKAPK2 mediates p38 and ERK signaling in vivo and is involved in various cellular processes such as stress and inflammatory responses, nuclear export, gene expression regulation, and cell proliferation. It encodes a member of the Ser/Thr protein kinase family and is regulated through direct phosphorylation by p38 MAP kinase. Heat shock protein HSP27 is one of its known substrates. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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