Thermo Fisher Scientific BCL2A1 Recombinant Rabbit Monoclonal Antibody (23GB4820)
인간 BCL2A1 단백질을 인식하는 재조합 토끼 단클론 항체. Western blot과 Flow cytometry에 적합. HEK293F 발현 시스템 사용, 액상 형태로 제공. 항-아폽토시스 관련 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Flow Cytometry (Flow)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB4820 |
| Immunogen | A synthesized peptide derived from human BCL2A1 (1-60AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Bcl-2 related Protein A1 is a member of the BCL-2 protein family. These proteins form hetero- or homodimers and act as anti- and pro-apoptotic regulators involved in various cellular processes such as embryonic development, homeostasis, and tumorigenesis.
This protein reduces the release of pro-apoptotic cytochrome c from mitochondria and blocks caspase activation. It is a direct transcription target of NF-kappa B in response to inflammatory mediators and is up-regulated by extracellular signals such as GM-CSF, CD40, phorbol ester, TNF, and IL-1, suggesting a cytoprotective function essential for lymphocyte activation and cell survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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