Thermo Fisher Scientific GSTM1 Recombinant Rabbit Monoclonal Antibody (23GB4940)
GSTM1 단백질을 인식하는 토끼 단클론 항체로, Western blot과 유세포분석에 적합합니다. HEK293F 시스템에서 발현된 재조합 항체이며, 인간, 생쥐, 랫트에 반응합니다. 친화 크로마토그래피로 정제되었고, PBS/glycerol 완충액에 보존됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB4940 |
| Immunogen | A synthesized peptide derived from human Glutathione S Transferase mu (100–152AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. Eight distinct classes of soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta.
This gene encodes a glutathione S-transferase belonging to the mu class, which functions in the detoxification of electrophilic compounds such as carcinogens, therapeutic drugs, environmental toxins, and oxidative stress products via conjugation with glutathione.
The mu class genes are located in a cluster on chromosome 1p13.3 and are highly polymorphic, influencing susceptibility to toxins and carcinogens as well as drug efficacy. Null mutations in this gene are associated with increased cancer risk due to heightened sensitivity to environmental toxins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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