Thermo Fisher Scientific CD34 Monoclonal Antibody (5A6)
인간 CD34 단백질을 인식하는 Mouse IgG1 단클론 항체로, 줄기세포 표지 및 CD34 관련 연구에 적합. Western blot과 ELISA에 사용 가능하며, 액상 형태로 제공되고 PBS buffer에 보존. 연구용으로만 사용 가능.
- 카탈로그번호
- H00000947-M02
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5A6 |
| Immunogen | CD34 (NP_001764, 32–141 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SLDNNGTATP ELPTQGTFSN VSTNVSYQET TTPSTLGSTS LHPVSQHGNE ATTNITETTV KFTSTSVITS VYGNTNSSVQ SQTSVISTVF TTPANVSTPE TTLKPSLSPG
Target Information
CD34 is a highly glycosylated monomeric surface protein (MW 111–115 kDa) expressed on various stem cell populations. It acts as a stem cell marker with reversible expression on human hematopoietic stem cells. CD34 may function as a receptor mediating endocytosis and regulating adhesion, differentiation, and proliferation of hematopoietic stem cells.
It likely facilitates attachment to the bone marrow extracellular matrix or stromal cells and may serve as a scaffold for lineage-specific glycans, enabling interaction with lectins. CD34 also presents carbohydrate ligands to selectins and is phosphorylated by protein kinase C, suggesting a role in signal transduction.
Diseases associated with CD34 dysfunction include dermatofibrosarcoma and neurofibroma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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