Thermo Fisher Scientific p120/Catenin, delta-1 (CTNND1) Recombinant Rabbit Monoclonal Antibody (CTNND1, 4383R)
Recombinant rabbit monoclonal antibody specific for human CTNND1 (p120/Catenin, delta-1). Optimized for IHC (paraffin) applications. High purity (Protein A/G). Supplied as liquid, 1 mg/mL in PBS. For research use only.
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Thermo Fisher Scientific p120/Catenin, delta-1 (CTNND1) Recombinant Rabbit Monoclonal Antibody (CTNND1, 4383R)
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | CTNND1, 4383R |
| Immunogen | Recombinant fragment (around aa900–1,000) of human CTNND1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For immunohistochemistry on PFA-fixed tissues, incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Delta 1 Catenin is an efficient tyrosine kinase substrate implicated in cell transformation by SRC and in ligand-induced receptor signaling through EGF, PDGF, CSF-1, and ERBB2 receptors.
Catenins associate with cadherins to form a complex linked to the actin filament network, which is essential for cadherin-mediated cell adhesion.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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