Thermo Fisher Scientific OASL Polyclonal Antibody
OASL 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot, ICC/IF, ELISA에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2.5 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | OASL antibody raised against a 17 amino acid peptide near the amino terminus of human OASL (within the first 50 amino acids). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718663 |
Target Information
2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to RNA degradation and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a conserved family of interferon-induced enzymes. The predicted 514-amino acid human p59OASL (OAS-like) protein shares a conserved N-terminal domain with other OASs, while the C-terminal portion contains two ubiquitin-like domains. p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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