Thermo Fisher Scientific S100A10 Polyclonal Antibody
Human S100A10 단백질을 인식하는 Sheep 유래 Polyclonal 항체. ELISA에 적합하며, 액상 형태로 제공. Affinity chromatography로 정제되어 높은 특이성과 재현성을 보장. 연구용으로만 사용 가능.
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- PA175390
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- pk
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Applications
- ELISA (ELISA)
Tested Dilution: 5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant human S100A10 (amino acids 1–97, UniProt ID: P60903-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2183348 |
Target Information
The S-100 family of calcium-activated proteins interacts with various target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II. This association is not required for plasma membrane localization or for binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B virus (Hep B) polymerase, facilitating partial nuclear localization and suggesting a role in viral replication in conjunction with intracellular calcium.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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