Thermo Fisher Scientific CDH4 Monoclonal Antibody (OTI1B7), TrueMAB
CDH4 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 적합. Human 시료 반응성. Lyophilized 형태로 제공되며, PBS buffer에 trehalose 포함. 재구성 후 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications
- Western Blot (WB): 1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 170–428 of human CDH4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CDH4 is a classical cadherin belonging to the cadherin superfamily. It encodes a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region, and a conserved cytoplasmic tail.
Studies in chicken and mouse suggest roles in brain segmentation, neuronal outgrowth, and kidney and muscle development.
Notably, CDH4 forms stable cis-heterodimers with cadherin 2, providing evidence for cadherin heterodimerization.
Three transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without authorization.
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