Thermo Fisher Scientific IBTK Polyclonal Antibody
IBTK 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 ELISA에 사용 가능. Human 시료에 반응하며, 액상 형태로 제공됨. Affinity Chromatography로 정제되어 고순도 확보. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 900–1200 of human IBTK (NP_0563402) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.40 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805918 |
Product Specific Information
Immunogen sequence:
GLNMAALLEA RSLDVLSDGV LKDLSEFYRK MIPAMDRRVI TPYQDGPDIS YLEVEDGDIF LKEEINMEQN HSETMFKKAK TKAKKKPRKR SDSSGGYNLS DIIQSPSSTG LLKSGKTNSV ESLPELLTSD SEGSYAGVGS PRDLQSPDFT TGFHSDKIEA KVKPYVNGTS PVYSREDLKP WEKSPILKIS APQPIPSNRI DTTSSASWVA GSFSPVSPPV VDLRTIMEIE ESRQKCGATP KSHLGKTVSH GVKLSQKQRK MIALTTKENN SGMNSMETVL FTPSKAPKPV NAWASSLHSV S
Positive Samples: Jurkat, HepG2
Cellular Location: Cytoplasm, Membrane, Nucleus, Peripheral membrane protein
Target Information
The protein encoded by this gene binds to Bruton’s tyrosine kinase (BTK) and downregulates BTK’s kinase activity. It also disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription.
⚠ WARNING:
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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