Thermo Fisher Scientific DKK2 Polyclonal Antibody
DKK2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, WB, ICC/IF, ELISA에 사용 가능. 인간 시료 반응성. 합성 펩타이드 면역원 기반. 액상 형태로 -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 100 to C-terminus of human DKK2 (NP_055236.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.84 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805922 |
Product Specific Information
Immunogen sequence:
CMVCRRKKKR CHRDGMCCPS TRCNNGICIP VTESILTPHI PALDGTRHRD RNHGHYSNHD LGWQNLGRPH TKMSHIKGHE GDPCLRSSDC IEGFCCARHF WTKICKPVLH QGEVCTKQRK KGSHGLEIFQ RCDCAKGLSC KVWKDATYSS KARLHVCQKI
Positive Samples: A-549, NCI-H460
Target Information
The DKK2 gene encodes a secreted protein belonging to the dickkopf family. It contains two cysteine-rich regions and participates in embryonic development via interactions with the Wnt signaling pathway. Depending on the cellular context and cofactors such as kremen 2, DKK2 can act as either an agonist or antagonist of Wnt/β-catenin signaling. Its activity is modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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