Thermo Fisher Scientific ADAMTS1 Monoclonal Antibody (OTI4E3), TrueMAB
ADAMTS1 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 IHC(P) 검증 완료. Human 시료 반응성, Lyophilized 형태, preservative-free 구성. 연구용으로 항체 결합 및 conjugation 실험에 적합.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E3 |
| Immunogen | Human recombinant protein fragment (aa 412–644 of human ADAMTS1, produced in E. coli) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ADAMTS-1 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family.
These proteins share modules such as a propeptide region, metalloproteinase domain, disintegrin-like domain, and thrombospondin type 1 (TS) motif.
ADAMTS-1 has two disintegrin loops and three C-terminal TS motifs and exhibits anti-angiogenic activity.
Its expression may be associated with inflammatory processes and cancer cachexia, and it is likely essential for normal growth, fertility, and organ morphology and function.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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