Thermo Fisher Scientific PRDM8 Polyclonal Antibody
Rabbit에서 유래한 PRDM8 폴리클로날 항체로, 비결합형 액상 형태이며 농도는 0.05 mg/mL입니다. 히스톤 메틸트랜스퍼레이스 연구에 적합하며, 신경 발달 및 스테로이드 생성 관련 유전자 연구에 활용됩니다. 연구용으로만 사용 가능합니다.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PRDM8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664891 |
Product Specific Information
Immunogen sequence:
RCPKRLHSADI SPQDEQGGGV GTKDHGGGGG GGKDQQQQQQ EAPLGPGPKF CKAGPLHHYP SPSPESSNPS
Highest antigen sequence identity to the following orthologs:
- Mouse: 78%
- Rat: 72%
Target Information
Probable histone methyltransferase, preferentially acting on Lys-9 of histone H3. Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR.
Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation. In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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