Thermo Fisher Scientific PTPRM Monoclonal Antibody (SK15)
PTPRM 단백질을 인식하는 SK15 클론의 마우스 단일클론 항체. Western blot과 Immunoprecipitation에 적합. 인간 PTP Mu 면역원으로 제작. 액상 형태로 제공되며 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2.5 µg/mL |
| Immunoprecipitation (IP) | 1 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SK15 |
| Immunogen | Mice were immunized with human PTP Mu and fusing the splenocytes with Sp2/0 mouse myeloma cells. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_1960056 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, representing a receptor-type PTP. The extracellular region contains a MAM domain, an Ig-like domain, and four fibronectin type III-like repeats.
It mediates cell-cell aggregation through interaction with another molecule of this PTP on adjacent cells and can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for downstream signaling in response to cell-cell adhesion.
Alternative splicing results in multiple transcripts encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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