Thermo Fisher Scientific RET Monoclonal Antibody (OTI5C5), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The receptor tyrosine kinase RET is a member of the cadherin superfamily and plays an essential role in neural crest development. RET can undergo oncogenic activation by cytogenetic rearrangement and transduces signals for cell growth and differentiation.
Mutations in the RET gene are associated with multiple endocrine neoplasia types IIA and IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been identified, with additional variants described but not biologically confirmed.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.