Thermo Fisher Scientific Neurogenin 2 Recombinant Rabbit Monoclonal Antibody (15H30L21)
Neurogenin 2 단백질을 인식하는 재조합 토끼 단클론 항체로, WB 및 ICC/IF에 적합합니다. 높은 특이성과 민감도, 로트 간 일관성 및 동물 유래 성분이 없는 포뮬레이션을 제공합니다. 인간 및 생쥐 반응성이 검증되었습니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 15H30L21 |
| Immunogen | Protein corresponding to Human NEUROG2 (aa 1–272) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633092 |
Product Specific Information
This antibody is predicted to react with Monkey, Dog, Bovine, and Rabbit.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Neurogenin-2 is a member of the neurogenin subfamily of basic helix-loop-helix (bHLH) transcription factor genes that play an important role in neurogenesis from migratory neural crest cells.
During mouse neurogenesis, Ngn2 and Ngn1 are expressed in distinct progenitor populations in the central and peripheral nervous systems. Mutation analyses demonstrate that Ngn1 is required for the determination of neuronal precursors for proximal cranial sensory ganglia, while Ngn2 is necessary for the determination of precursors for epibranchial placode-derived sensory neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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