Thermo Fisher Scientific PTPRB Polyclonal Antibody
PTPRB 단백질에 특이적인 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 50% 글리세롤 보존 용액에 포함. 세포 신호 조절 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:50–400 | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–100 | - |
| Immunocytochemistry (ICC/IF) | 1:50–500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Tyrosine Phosphatase Receptor Type B (amino acids 1214–1463 of target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903871 |
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family, which regulates various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This receptor-type PTP contains an extracellular domain with multiple fibronectin type III repeats, a transmembrane segment, and an intracellular catalytic domain. It interacts with neuronal receptors and cell adhesion molecules (e.g., contactin, tenascin C) as well as sodium channels, suggesting a role in regulating sodium channel phosphorylation, cell adhesion, neurite growth, and neuronal differentiation.
Alternate transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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