Thermo Fisher Scientific GPNMB Monoclonal Antibody (7C10E5)
GPNMB 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, WB, IHC, ELISA에 적합합니다. 정제된 재조합 인간 GPNMB(aa 31-260)를 면역원으로 사용하였으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. Protein G 정제, PBS 버퍼 및 sodium azide 포함.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7C10E5 |
| Immunogen | Purified recombinant fragment of human GPNMB (aa: 31–260) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898444 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
The protein encoded by this gene is a type I transmembrane glycoprotein homologous to pMEL17, a melanocyte-specific protein. GPNMB is expressed in lowly metastatic human melanoma cell lines and xenografts but not in highly metastatic ones. It may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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