Thermo Fisher Scientific SYP Monoclonal Antibody (OTI2D8), TrueMAB
인간 Synaptophysin을 인식하는 OTI2D8 클론 단일클론 항체로, WB, IHC, ICC/IF에 사용 가능. 무보존제, 동결건조 형태로 제공되며 재구성 후 1 mg/mL 농도 유지. 신경말단 및 신경내분비종양 표지에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:6000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D8 |
| Immunogen | Full length human recombinant protein of human SYP produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
- For conjugation experiments, an additional desalting step is recommended (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Synaptophysin is a calcium-binding integral membrane glycoprotein found in presynaptic vesicles of nearly all neurons. It has four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting a role in synaptic vesicle endocytosis. Synaptophysin is involved in regulating short-term and long-term synaptic plasticity and is widely used as a marker for nerve terminals and neuroendocrine tumor differentiation. Mutations in the gene can result in X-linked mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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