Thermo Fisher Scientific Cathepsin K Polyclonal Antibody
Cathepsin K 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Affinity chromatography로 정제되었으며, -20°C에서 보관. 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CTSK (Accession P43235), corresponding to amino acid residues V11–N61. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851885 |
Product Specific Information
This antibody detects endogenous levels of total CTSK.
Target Information
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. It belongs to the peptidase C1 family and is predominantly expressed in osteoclasts. It is also expressed in some human breast cancers, potentially contributing to tumor invasiveness. Mutations in this gene cause pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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