Thermo Fisher Scientific COX5B Polyclonal Antibody
COX5B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, Flow cytometry 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제된 고품질 항체로, 인간 시료 반응성. 연구용으로만 사용.
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Thermo Fisher Scientific COX5B Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Flow Cytometry (Flow) | 1:50–1:100 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within Human COX5B aa 50–99 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2901118 |
Product Specific Information
Positive controls: 293 cell lysates, human liver tissue, human liver carcinoma tissue, human kidney tissue, human small intestine tissue, HepG2.
Target Information
The cytochrome c oxidase (COX) family of proteins functions as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, resulting in the production of water. The mammalian COX apoenzyme is a dimer composed of 13 subunits, both mitochondrial and nuclear. Found in the inner mitochondrial membrane, COX5 is the heme A-containing chain that converts oxygen and hydrogen into water. Two isoforms exist: COX5a and COX5b. Under high oxygen conditions, COX5a transcription increases, while under hypoxic conditions, COX5b transcription is up-regulated to maximize COX apoenzyme turnover.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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