Thermo Fisher Scientific AGTR1 Monoclonal Antibody (338CT11.2.5)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:100-1:250

-

Product Specifications

Host/Isotype

Mouse / IgM, kappa

Class

Monoclonal

Type

Antibody

Clone

338CT11.2.5

Immunogen

KLH conjugated synthetic peptide between 211-240 amino acids from the Central region of human AGTR1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AGTR1,uniProtId:P30556-1,ncbiNodeId:9606,antigenRange:211-240,antigenLength:359,antigenImageFileName:MA5-37535_AGTR1_P30556-1_House_mouse.svg,antigenImageFileNamePDP:MA5-37535_AGTR1_P30556-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Lot-Specific

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

Target Information

AGTR1 is known as Angiotensin II Type 1 Receptor. Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. And it acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. Moreover, this gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.