Thermo Fisher Scientific IL6 Monoclonal Antibody (4B12)
IL6 단백질을 표적으로 하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 4B12). Western Blot, ICC/IF, ELISA에 적합하며 인간 시료 반응성. PBS 기반 액상 형태, 보존제 없음. 연구용 전용.
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Thermo Fisher Scientific IL6 Monoclonal Antibody (4B12)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4B12 |
| Immunogen | IL6 (NP_000591, 29 a.a.–212 a.a.) full-length recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SPVPPGEDSK DVAAPHRQPL TSSERIDKQI RYILDGISAL RKETCNKSNM CESSKEALAE NNLNLPKMAE KDGCFQSGFN EETCLVKIIT GLLEFEVYLE YLQNRFESSE EQARAVQMST KVLIQFLQKK AKNLDAITTP DPTTNASLLT KLQAQNQWLQ DMTTHLILRS FKEFLQSSLR ALRQM
Target Information
IL-6 encodes a cytokine involved in inflammation and B cell maturation. It acts as an endogenous pyrogen and is secreted at sites of acute and chronic inflammation. IL-6 induces transcriptional inflammatory responses via the interleukin 6 receptor alpha.
This gene is associated with various inflammation-related diseases, including diabetes mellitus, systemic juvenile rheumatoid arthritis, Kaposi Sarcoma, and Rheumatoid Arthritis. Elevated IL-6 levels have been observed in viral infections, including COVID-19.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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