Thermo Fisher Scientific IFNAR1 Polyclonal Antibody
IFNAR1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC(P) 및 ICC/IF 실험에 적합하며, 인간 Interferon-alpha/beta Receptor α-chain 유래 합성 펩타이드로 제작. 고순도, 액상 형태, -20°C 보관.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human Interferon-alpha/beta Receptor alpha chain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555103 |
Target Information
Interferons are widely used therapeutic agents because of their anti-tumor and antiviral effects and their modulatory effects on the immune system (Biron, 2001; Kirkwood, 2002). These cytokines produce their effects by binding to the Type I Interferon Receptor (IFNAR1). Downregulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This downregulation is thought to be influenced by phosphorylation of Serine 535 and 539 in IFNAR1 (Kumar et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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