Thermo Fisher Scientific NBN Monoclonal Antibody (OTI2E10), TrueMAB
Human NBN 단백질을 표적하는 Mouse IgG1 단클론 항체로, WB 및 IHC(P) 분석에 적합합니다. TrueMAB 포맷으로 높은 특이성과 재현성을 제공합니다. 1 mg/mL 농도의 액상 형태로, PBS/BSA/glycerol buffer에 보관됩니다.
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Thermo Fisher Scientific NBN Monoclonal Antibody (OTI2E10), TrueMAB
Applications and Tested Dilution
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E10 |
| Immunogen | Human recombinant protein fragment (aa 183–460 of human NBN) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The p95 gene (identical to NBS1 and nibrin) is part of the hMre11/hRad50 double-strand break complex. This complex is associated with Nijmegen breakage syndrome, an autosomal recessive disorder characterized by increased cancer incidence, cell cycle checkpoint defects, and sensitivity to ionizing radiation. It plays a key role in linking double-strand break repair to cell cycle checkpoint functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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