Thermo Fisher Scientific PDE2A Polyclonal Antibody
Thermo Fisher Scientific의 PDE2A 폴리클로날 항체로 랫트 PDE2A 단백질을 인식합니다. Western blot에 적합하며, 비결합형 액상 형태로 제공됩니다. 높은 종간 상동성을 가지며, 뇌 조직 연구 및 PDE2A 관련 생리 기능 분석에 유용합니다.
- 카탈로그번호
- PA570211
- 판매단위
- pk
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Thermo Fisher Scientific PDE2A Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of rat PDE2A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691031 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%
Dog: 100%
Guinea Pig: 100%
Human: 100%
Mouse: 100%
Rat: 100%
Target Information
PDE2A (phosphodiesterase 2A) is a 100 kD cyclic nucleotide phosphodiesterase (PDE).
Three isoforms of PDE2A have been reported (PDE2A1, PDE2A2, and PDE2A3), which arise from a single gene by alternative splicing events.
PDE2A can degrade both cAMP and cGMP, but degrades cGMP with greater efficacy.
It is expressed in a variety of tissue types, with greatest expression in the brain, localized in the cerebellum and neocortex.
PDE2A has been implicated in penile erectile dysfunction and in the regulation of fluid and inflammatory cell transport across the endothelial cell barrier.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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