Thermo Fisher Scientific FGR Monoclonal Antibody (6G2)
Human 및 Mouse 시료에서 FGR 단백질 검출용 Mouse monoclonal antibody. Western blot, IHC, ELISA에 적합하며 비결합형 액상 형태로 제공. 장기 보관 시 -20°C에서 보관 권장.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6G2 |
| Immunogen | Purified recombinant fragment of human FGR expressed in E. Coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% Sodium Azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet Ice |
| RRID | AB_10982526 |
Product Specific Information
MA5-15490 targets FGR in indirect ELISA, IHC, and WB applications and shows reactivity with human and mouse samples.
The immunogen is a purified recombinant fragment of human FGR expressed in E. coli.
MA5-15490 detects FGR, which has a predicted molecular weight of approximately 56 kDa.
Target Information
FGR is a SRC-related kinase present in hematopoietic cells. It participates in multiple signaling pathways, including the integrin pathway and downstream of chemokine and cytokine receptors.
This protein contains N-terminal sites for myristylation and palmitoylation, a PTK domain, and SH2/SH3 domains that mediate protein-protein interactions with phosphotyrosine-containing and proline-rich motifs.
FGR localizes to plasma membrane ruffles and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway.
Infection with Epstein-Barr virus results in the overexpression of this protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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