Thermo Fisher Scientific MP68 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MP68. Recombinant protein control fragment (Product #RP-100172). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MP68,uniProtId:P56378-1,ncbiNodeId:9606,antigenRange:12-58,antigenLength:58,antigenImageFileName:PA5-63636_MP68_P56378-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63636_MP68_P56378-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644069

Product Specific Information

Immunogen sequence: PMKPYYTKVY QEIWIGMGLM GFIVYKIRAA DKRSKALKAS APAPGHH

Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 76%.

Target Information

MP68, also known as PLPM or C14orf2 (chromosome 14 open reading frame 2), is a 58 amino acid mitochondrial protein that belongs to the small mitochondrial proteolipid family. The gene encoding MP68 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer`s disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder alpha1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.