Thermo Fisher Scientific HEY1 Polyclonal Antibody
Rabbit polyclonal antibody against mouse HEY1 protein. Validated for Western blot at 2–4 µg/mL. Recognizes amino acids 50–100 of HEY1. Supplied as liquid, protein A purified, in PBS with BSA and sodium azide. For research use only.
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Applications
Western Blot (WB)
- Tested dilution: 2–4 µg/mL
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A portion of amino acids 50–100 of mouse Hey1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540984 |
Target Information
Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1) belongs to the HEY family and is a Notch signaling pathway protein. It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. HEY1 acts as a downstream effector of Notch signaling and may be required for cardiovascular development. It functions as a transcriptional repressor, binding preferentially to the canonical E-box sequence 5'-CACGTG-3', and represses transcription by the cardiac activators GATA4 and GATA6. HEY1 is also expressed during development of the nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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