Thermo Fisher Scientific LYK5 Polyclonal Antibody
Human STRADA 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 실험에 적합합니다. Protein A 및 항원 친화 크로마토그래피로 정제되었으며, PBS buffer에 ProClin 300이 포함되어 있습니다. 연구용으로만 사용 가능합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the N-terminus of the Human STRADA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS, pH 7 |
| Contains | 0.03% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2788301 |
Product Specific Information
This antibody has specificity for Human STRADA.
Target Information
LYK5 (STE20-related Adaptor Protein, STRAD)
Gene locus: 17q23.3
Members of the STE-20 like kinase family are known to stimulate MAPK pathways by directly activating MAPKKK. STRAD is a pseudokinase containing a STE-20 like kinase domain but lacks residues required for catalytic activity. It specifically binds to LKB1 and regulates its tumor suppressor activities. STRAD functions as an upstream activator of LKB1 and directs its subcellular localization by anchoring it in the cytoplasm. The STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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