Thermo Fisher Scientific GRSF1 Polyclonal Antibody
GRSF1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, IHC, ICC, ELISA에 사용 가능. 인간, 생쥐, 랫트에 반응하며 고순도 Affinity chromatography로 정제됨. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids 100–200 of human GRSF1 (NP_0020834) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5.05 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901440 |
Product Specific Information
- Positive Samples: HeLa, mouse kidney
- Immunogen sequence:
SLLPQSLAAA AAVPTRSYSQ ESKTTYLEDL PPPPEYELAP SKLEEEVDDV FLIRAQGLPW SCTMEDVLNF FSDCRIRNGE NGIHFLLNRD GKRRGDALIE M
Target Information
G-rich sequence factor 1 (GRSF1) is a regulator of post-transcriptional mitochondrial gene expression. It is required for assembly of the mitochondrial ribosome and for recruitment of mRNA and IncRNA.
GRSF1 binds RNAs containing the 14-base G-rich element and preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA, including ND6 mRNA and long non-coding RNAs for MT-CYB and MT-NDS, each containing multiple consensus binding sequences.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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