Thermo Fisher Scientific Inhibin, alpha (INHA) Recombinant Rabbit Monoclonal Antibody (INHA, 6598R)
Human INHA 단백질을 인식하는 Recombinant Rabbit Monoclonal 항체. IHC(P)에서 1–2 µg/mL 권장. HEK293 발현, Protein A/G 정제, PBS/BSA buffer. 4°C 보관, 연구용 전용.
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- 3623-RBM8-P1
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | INHA, 6598R |
| Immunogen | Recombinant fragment of human Inhibin alpha protein (around aa 233–362) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For IHC (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin negatively regulates gonadal stromal cell proliferation and exhibits tumor-suppressor activity. Serum inhibin levels correlate with granulosa-cell tumor size and can serve as a biomarker for primary and recurrent disease. In prostate cancer, expression of the inhibin alpha-subunit gene is suppressed and undetectable in poorly differentiated tumor cells. Expression varies across tissues, suggesting inhibin functions as both a growth/differentiation factor and a hormone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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