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Thermo Fisher Scientific CD279 (PD-1) Monoclonal Antibody (eBioJ105 (J105)), PE, eBioscience

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인간 및 원숭이 PD-1 단백질을 인식하는 eBioJ105 클론 단일클론 항체로, Flow Cytometry용으로 최적화됨. PE 형광표지로 565/576 nm에서 Excitation/Emission. 4°C 암소 보관, 동결 금지. PBS 기반 완충액에 0.2% BSA 및 0.09% sodium azide 함유.

카탈로그번호: 12-2799-4x (2개 옵션)
브랜드: Thermo Fisher Scientific
카테고리: Monoclonal Antibodies
판매단위: pk

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Thermo Fisher Scientific 12-2799-42 CD279 (PD-1) Monoclonal Antibody (eBioJ105 (J105)), PE, eBioscience 100 tests pk판매 단위 pk ·

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477,100원VAT 포함 524,810원

Thermo Fisher Scientific 12-2799-41 CD279 (PD-1) Monoclonal Antibody (eBioJ105 (J105)), PE, eBioscience 25 tests pk판매 단위 pk ·

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242,500원VAT 포함 266,750원

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Thermo Fisher Scientific · Thermo Fisher Scientific CD279 (PD-1) Monoclonal Antibody (eBioJ105 (J105)), PE, eBioscience

Thermo Fisher Scientific CD279 (PD-1) Monoclonal Antibody (eBioJ105 (J105)), PE, eBioscience™

Applications

Flow Cytometry (Flow)
Tested Dilution: 5 µL (0.5 µg)/test
View 30 publications

Product Specifications

항목	내용
Species Reactivity	Human, Rhesus monkey
Published Species	Human, Mouse, Non-human primate, Rhesus monkey
Host / Isotype	Mouse / IgG1, kappa
Recommended Isotype Control	Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PE, eBioscience™
Class	Monoclonal
Type	Antibody
Clone	eBioJ105 (J105)
Conjugate	PE
Excitation / Emission Max	565 / 576 nm
Form	Liquid
Concentration	5 µL/Test
Purification	Affinity chromatography
Storage Buffer	PBS, pH 7.2, with 0.2% BSA
Contains	0.09% sodium azide
Storage Conditions	4°C, store in dark, DO NOT FREEZE
Shipping Conditions	Ambient (domestic); Wet ice (international)
RRID	AB_10597751

Available Formats

Unconjugated
APC
APC-eFluor 780
Biotin
Brilliant UV 615, 661, 737, 805
Brilliant Violet 421, 480, 650, 711, 786
PE-Cyanine5, PE-Cyanine7, PE-eFluor 610
PerCP-eFluor 710
Super Bright 436, 600, 645, 702, 780
Request custom conjugation

Product Specific Information

The J105 monoclonal antibody reacts with human PD-1 (programmed death-1), a 55 kDa member of the CD28 immunoglobulin superfamily. PD-1 contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease. PD-1 is expressed predominantly on activated T and B lymphocytes.
Two ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC), have been identified, showing overlapping functions and expression patterns.

Costaining experiments suggest eBioJ105 recognizes a different epitope than MIH4 (Product #11-9969).

Applications Reported: Flow cytometric analysis
Applications Tested: Pre-titrated and validated on PHA-stimulated human peripheral blood cells

Recommended use: 5 µL (0.5 µg)/test
A test = antibody amount for staining 100 µL cell sample (10⁵–10⁸ cells/test)

Excitation: 488–561 nm
Emission: 578 nm
Compatible lasers: Blue, Green, Yellow-Green
Filtration: 0.2 µm post-manufacturing filtered

Target Information

PD-1 (PDCD-1) is an inhibitory receptor expressed on activated T cells that binds PD-L1 and PD-L2 on antigen-presenting cells to regulate immune activation. Binding of PD-1 to its ligands inhibits T-cell activation in the absence of danger signals such as LPS. PD-1 deficiency leads to hyperactivated immune responses and autoimmune disease.
Despite its predicted molecular weight, PD-1 often migrates at a higher apparent molecular weight in SDS-PAGE.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.