Thermo Fisher Scientific eIF4A2 Polyclonal Antibody
Human, Mouse, Rat 반응성을 가진 Rabbit Polyclonal eIF4A2 항체로, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. KLH 결합 합성 펩타이드(aa 141–240)로 면역화. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Thermo Fisher Scientific eIF4A2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human eIF4A2, amino acids 141–240 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
eIF4A2 is a 407 amino acid ATP-dependent RNA helicase belonging to the DEAD box helicase family. It contains one helicase ATP-binding domain and a helicase C-terminal domain. As a subunit of the eIF4F complex, eIF4A2 functions as a protein synthesis initiation factor, facilitating the binding of mRNA to the 43S pre-initiation complex of ribosomes.
Human eIF4A2 interacts with the NS5B protein of Hepatitis C virus (HCV), aiding genomic RNA synthesis by unwinding the secondary structure of the HCV genome. It is ubiquitously expressed in most normal tissues, though expression levels vary.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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