Thermo Fisher Scientific CD42b Polyclonal Antibody
Thermo Fisher Scientific CD42b Polyclonal Antibody는 인간 및 생쥐 시료에서 CD42b 단백질을 검출하는 고품질 항체입니다. Western blot과 IHC(P) 실험에 적합하며, 고순도 Affinity chromatography로 정제되었습니다. 액상 형태로 제공되며 PBS/glycerol buffer에 보관됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GP1BA (Accession P07359), corresponding to amino acid residues R606–L652 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2852488 |
Product Specific Information
Antibody detects endogenous levels of total CD42b.
Target Information
CD42b is a platelet activation marker involved in coagulation and platelet aggregation. It interacts with extracellular matrix and adhesion molecules, and its expression is regulated by VEGF and PDGF. CD42b forms part of the GPIb-IX-V receptor complex, essential for platelet-rich thrombus formation by binding to von Willebrand factor (VWF) and other coagulation factors. It is expressed on platelets and megakaryocytes in bone marrow. Mutations in CD42b are associated with Bernard-Soulier syndrome and platelet-type von Willebrand disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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