Thermo Fisher Scientific Calpain 10 Polyclonal Antibody
Calpain 10 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 0.48 mg/mL 농도의 액상 형태입니다. 인체 시료에 반응하며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 186–517 of Human Calpain 10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.48 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2547348 |
Product Specific Information
- Recommended positive control: HeLa
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Calpains, including Calpain 1 (CAPN1), are calcium-activated neutral proteases that are nonlysosomal and intracellular cysteine proteases. Mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes are heterodimers with distinct large catalytic subunits and a common small regulatory subunit.
This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been identified.
Diseases associated with CAPN1 include Spastic Paraplegia 76 (Autosomal Recessive) and Spasticity.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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