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Thermo Fisher Scientific Topoisomerase II alpha Recombinant Mouse Monoclonal Antibody (rTOP2A, 6569)
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Thermo Fisher Scientific Topoisomerase II alpha Recombinant Mouse Monoclonal Antibody (rTOP2A, 6569)

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Recombinant mouse monoclonal antibody targeting Topoisomerase II alpha (TOP2A). Validated for WB and IHC applications. High specificity for human and mouse TOP2A. Supplied as liquid form, 1 mg/mL, purified via Protein A/G. Suitable for research use only.

카탈로그번호
7153-MSM4-P1ABX
판매단위
pk
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마지막 업데이트 2025. 08. 03. 오후 04:51
Thermo Fisher Scientific 7153-MSM4-P1ABX Topoisomerase II alpha Recombinant Mouse Monoclonal Antibody (rTOP2A, 6569) 100 ug pk판매 단위 pk ·
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829,000원VAT 포함 911,900원

Thermo Fisher Scientific · Thermo Fisher Scientific Topoisomerase II alpha Recombinant Mouse Monoclonal Antibody (rTOP2A, 6569)

Applications

Western Blot (WB)

  • Assay-dependent

Immunohistochemistry (Paraffin) (IHC (P))

  • 0.5–1 µg/mL

Product Specifications

항목 내용
Species Reactivity Human, Mouse
Host / Isotype Mouse / IgG2a, kappa
Expression System HEK293 cells
Class Recombinant Monoclonal
Type Antibody
Clone rTOP2A, 6569
Immunogen Recombinant human Topoisomerase II alpha fragment (aa1352–1493)
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Protein A/G
Storage Buffer PBS, pH 7.4
Contains No preservative
Storage Conditions -20°C or -80°C if preferred
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
  • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer (pH 6.0) for 10–20 minutes, followed by cooling at room temperature for 20 minutes.

Target Information

Topoisomerase II alpha (Topo IIα) plays crucial roles in DNA synthesis, transcription, and chromosomal segregation during mitosis. It serves as a sensitive and specific marker of late S-, G2-, and M-phases in transformed and developmentally regulated normal cells. Additionally, Topo IIα is implicated in drug resistance of tumor cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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