Thermo Fisher Scientific CCDC36 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CCDC36. Recombinant protein control fragment (Product #RP-107695). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CCDC36,uniProtId:Q8IYA8-1,ncbiNodeId:9606,antigenRange:418-506,antigenLength:594,antigenImageFileName:PA5-84815_CCDC36_Q8IYA8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-84815_CCDC36_Q8IYA8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2791964

Product Specific Information

Immunogen sequence: LCDPREHLVI KQKDGTVEMR GKDKKQQPRK AHRAHRGRLI ASKQKQIPIQ TCKFNSKYQS PQPAISVPQS PFLGQQEPRA QPLHLQCPR

Target Information

Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.