Thermo Fisher Scientific NMI Monoclonal Antibody (OTI1A8), TrueMAB
인간 NMI 단백질(aa 1-223)에 특이적인 Mouse IgG2a 단일클론 항체. Western blot에 최적화되어 있으며, carrier-free 형태로 다양한 실험에 활용 가능. 고순도 친화크로마토그래피 정제, -20°C 보관. 연구용 전용 제품.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–223 of human NMI produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC, members of the oncogene Myc family, as well as other transcription factors with Zip, HLH, or HLH-Zip motifs.
NMI interacts with all STATs except STAT2, enhancing STAT-mediated transcription in response to cytokines IL2 and IFN-γ.
NMI mRNA shows low expression in most human tissues except brain and is highly expressed in myeloid leukemia cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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