Thermo Fisher Scientific BVES Polyclonal Antibody
Human BVES 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 용액에 40% glycerol 포함. 연구용으로 세포 간 접착 및 혈관 발달 관련 연구에 활용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human BVES. Recombinant protein control fragment (Product #RP-91074) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638644 |
Product Specific Information
- Immunogen sequence:
LNDPTLNDKK AKKLEHQLSL CTQISMLEMR NSIASSSDSD DGLHQFLRGT SSMSSLHVSS PHQRASAKMK PIEEGAEDDD DVFEPASPNT LKVHQLP - Highest antigen sequence identity to orthologs:
- Mouse: 79%
- Rat: 25%
Target Information
Blood vessel epicardial substance (BVES), also known as Popeye protein 1, is a transmembrane protein involved in cell-cell interactions and adhesion, particularly at tight junctions.
BVES consists of an extracellular amino-terminus, three transmembrane domains, and a cytoplasmic carboxyl-terminus.
It is expressed in the developing coronary vascular system, including the proepicardium, migrating epithelial epicardium, delaminated vasculogenic mesenchyme, and vascular smooth muscle cells.
BVES functions in directing development of heart, epithelial, and muscle cells during embryogenesis, and accumulates at cell-cell contact points such as filopodia and cell borders, promoting adhesion prior to E-cadherin arrival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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