Thermo Fisher Scientific BVES Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human BVES. Recombinant protein control fragment (Product #RP-91074). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BVES,uniProtId:Q8NE79-1,ncbiNodeId:9606,antigenRange:264-360,antigenLength:360,antigenImageFileName:PA5-53235_BVES_Q8NE79-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53235_BVES_Q8NE79-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2638644

Product Specific Information

Immunogen sequence: LNDPTLNDKK AKKLEHQLSL CTQISMLEMR NSIASSSDSD DGLHQFLRGT SSMSSLHVSS PHQRASAKMK PIEEGAEDDD DVFEPASPNT LKVHQLP

Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 25%.

Target Information

Blood vessel epicardial substance (BVES), also designated Popeye protein 1, is a transmembrane protein that plays a role in cell-cell interactions and adhesion, specifically at tight junctions. BVES is composed of an extracellular amino-terminus, three transmembrane domains and a cytoplasmic carboxyl-terminus. It is expressed in the developing coronary vascular system, specifically in the proepicardium, migrating epithelial epicardium, delaminated vasculogenic mesenchyme and vascular smooth muscle cells, where it functions to direct development in heart, epithelial and muscle cells during embryogenesis. BVES accumulates at points of cell-cell contact, such as filopodia and cell borders, and promotes adhesion prior to the arrival of E-cadherin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.