Thermo Fisher Scientific ARGBP2 Polyclonal Antibody
Human ARGBP2 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific ARGBP2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ARGBP2. Recombinant protein control fragment (Product #RP-95660). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638125 |
Product Specific Information
Immunogen sequence:
PERNSSLRAL RRSPLHQPLH PLPPDGAIHC PPYQNDCGRM PRSASFQDVD TANSSCHHQD RGGALQDRES PRSYSSTLTD MGRSAPRER
Highest antigen sequence identity to orthologs:
- Mouse: 78%
- Rat: 77%
Target Information
Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via SH3 domains at the carboxy end of these proteins.
ARGBP2 (Sorbin and SH3 domain containing 2 protein) has three C-terminal SH3 domains and an N-terminal SoHo domain that interacts with lipid raft proteins.
Its localization in epithelial and cardiac muscle cells suggests a role as an adapter protein assembling signaling complexes in stress fibers and linking Abl family kinases to the actin cytoskeleton.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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