Thermo Fisher Scientific MET/HGFR Monoclonal Antibody (4AT44)
상품 옵션 정보 | ||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
BSM-51002M | - | Thermo Fisher Scientific BSM-51002M MET/HGFR Monoclonal Antibody (4AT44) 100 ul pk | 재고문의 | pk | 529,000원 | - | 581,900원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:100-1:500
Immunohistochemistry (Paraffin) (IHC (P))
1:25
Immunocytochemistry (ICC/IF)
Assay-dependent
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
4AT44
Immunogen
This monoclonal antibody is generated from mice immunized with purified recombinant protein encoding the catalytic domain of human Met.
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
TBS with 1% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
MET (cMET) is a receptor-like tyrosine kinase whose dysregulation has been linked to many types of human malignancies. After activation of the ligand, MET interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3. There interactions lead to the activation of signaling cascades including RAS-ERK, PI3, kinase-AKT, and PLCgamma-PKC. MET plays a role in embryonic development including gastrulation, development of muscles and neurons, angiogenesis, and kidney formation. It also plays a role in adults including wound healing, organ regeneration, and tissue remodeling. MET has been linked to cancers including gastric, renal, and breast; therefore, making it a target for cancer therapeutics and diagnostic testing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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