Thermo Fisher Scientific Catenin, beta (p120) Monoclonal Antibody (CTNNB1, 2099)
인간 베타-카테닌(CTNNB1)을 인식하는 마우스 모노클론 항체로, IHC(P) 등 다양한 응용에 적합. 단백질 A/G로 정제된 액상 형태이며, 4°C 보관. 세포 부착 및 신호전달 연구에 유용.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CTNNB1, 2099 |
| Immunogen | Recombinant full-length human beta-Catenin (CTNNB1) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at room temperature for 20 min.
Target Information
Beta-catenin is an adherens junction (AJ) protein involved in cell-cell adhesion and epithelial layer maintenance. It interacts with E-cadherin and alpha-catenin to link the adhesion complex to the actin cytoskeleton. Beta-catenin also associates with cytoskeletal complexes containing adenomatous polyposis coli protein and microtubules, participating in signaling pathways such as Wnt/Wingless.
It is expressed in various hair follicle cell types and epithelial tissues. Dysregulation of beta-catenin is implicated in several cancers, including colorectal, ovarian, breast, liver, lung, gastric, prostate, and skin tumors. In the nucleus, beta-catenin co-activates Lef/Tcf transcription factors that regulate genes like cyclin D and c-myc, promoting cell proliferation and tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(관련 이미지가 있을 경우 이 섹션에 배치합니다.)
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific Catenin, beta (p120) Recombinant Mouse Monoclonal Antibody (rCTNNB1, 2173)
522,100원
Thermo Fisher Scientific
Thermo Fisher Scientific Catenin, beta (p120) Monoclonal Antibody (CTNNB1, 2099)
825,100원
Thermo Fisher Scientific
Thermo Fisher Scientific Catenin, beta (p120) Monoclonal Antibody (CTNNB1, 2099)
441,900원
Thermo Fisher Scientific
Thermo Fisher Scientific Catenin, beta (p120) Monoclonal Antibody (CTNNB1, 2099)
825,100원
Thermo Fisher Scientific
Thermo Fisher Scientific Catenin, beta (p120) Monoclonal Antibody (CTNNB1/2098)
900,300원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|